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xanthium strumarium var. canadense pollen extract
- Development stage
- Unknown
- Lead developer
- ALK Abelló
- Modality
- Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Percutaneous, Intradermal, Epicutaneous
01
Overview
Xanthium strumarium var. canadense pollen extract is a non-standardized allergenic biologic developed and manufactured by ALK-Abello. It is derived from the pollen of the Canada cocklebur (*Xanthium strumarium* var. *canadense*). The extract is utilized in clinical settings for the diagnosis (via skin testing) and treatment (via allergen immunotherapy) of allergic rhinitis, allergic conjunctivitis, and bronchial asthma triggered by sensitivity to cocklebur pollen. As an immunotherapy, it works by inducing immunological tolerance through repeated exposure to the allergen, shifting the immune response from a Th2-mediated allergic reaction to a Th1-mediated or regulatory T-cell response.
- Brand names
- Canada Cocklebur
- Other names
- Xanthium strumarium var. canadense pollenCanada cocklebur pollen extract
02
Targets
IgE (Immunoglobulin E)
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