xantinol nicotinate

Xantinol nicotinate is a pharmaceutical drug classified as a peripheral vasodilator, synthesized as an ester of xanthinol (a theophylline derivative) and nicotinic acid (niacin). It acts primarily by dilating blood vessels, which improves blood circulation, increases oxygen and glucose delivery to tissues—including the brain and extremities—and reduces blood viscosity, cholesterol, and fibrinogen in some patients. Xantinol nicotinate is used primarily in the management of peripheral vascular disease (PVD), cerebrovascular disorders, and related conditions such as intermittent claudication, memory disorders, Raynaud's disease, and diabetic angiopathy. Its mechanism is believed to involve facilitation of nicotinic acid cellular uptake by the xanthinol ion, enhancement of cell metabolism via NAD/NADP-related pathways, and improvement of microcirculation. It is available in both oral (tablet, capsule) and parenteral (injectable) forms, and was previously approved and marketed in various countries but is now discontinued or not widely available in many regions. Common adverse effects include flushing, sensation of warmth, dizziness, gastrointestinal symptoms, and palpitations[1][2][3][4][5][6][7][8][9].

Brand names

ComplamineComplaminComplamexCervas

Other names

xanthinol nicotinatexanthinol niacinate