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The XBB.1.5 vaccine is a type of vaccine developed to target the SARS-CoV-2 Omicron XBB.1.5 variant. It is available in various platforms, including mRNA-based, protein-based (e.g., Nuvaxovid), and inactivated vaccine formulations. The vaccine works by eliciting an immune response, primarily through the production of neutralizing antibodies and T-cell responses, against the spike protein of the XBB.1.5 variant. It is intended to prevent or mitigate COVID-19, particularly in the context of evolving SARS-CoV-2 variants. Studies have evaluated its immunogenicity, safety, and effectiveness in diverse populations, including older adults and immunocompromised individuals.
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