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XCEL-MT-OSTEO-BETA
- Development stage
- Phase 2
- Lead developer
- Xcelia
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraosseous, Surgical Implantation, Intralesional
01
Overview
XCEL-MT-OSTEO-BETA is a tissue-engineered medicinal product (ATMP) consisting of ex vivo expanded allogenic adult mesenchymal stem cells (MSCs) seeded onto an allogenic human bone tissue scaffold. Developed by the Banc de Sang i Teixits (BST) in Spain, it is designed to promote bone regeneration and healing in complex fractures, specifically proximal femur (hip) fractures in elderly patients. The product combines the osteogenic potential of stem cells with the structural support and osteoconductive properties of allograft bone. It has been investigated in pilot clinical trials to evaluate its safety and preliminary efficacy in improving surgical outcomes and bone union compared to standard treatments.
- Other names
- ex vivo expanded allogenic adult stem cells combined with allogenic human bone tissue
02
Targets
IGF-1R (Insulin-like growth factor 1 receptor)INSR (Insulin receptor)
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