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XED-60 is an investigational small molecule topical ophthalmic agent developed by Lion Corporation for the treatment of dry eye disease. It is currently in Phase 2 clinical development in Japan, where it is being evaluated as an eye drop formulation administered six times daily for a duration of four weeks. The clinical trial (jRCT1080222777) focuses on patients aged 15 years and older diagnosed with dry eye according to the Japanese Dry Eye Research Group criteria. While the specific molecular target of XED-60 has not been publicly disclosed, it is categorized as a potential mucin production promoter intended to stabilize the tear film and improve the health of the ocular surface.
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