Drug intelligence / Profile preview

xeroderris stuhlmannii extract

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xeroderris stuhlmannii extract is a botanical plant extract derived from *Xeroderris stuhlmannii*, a medicinal plant used traditionally in Zimbabwe for type 2 diabetes mellitus and related complications. The available published evidence is preclinical and centers on phytochemical constituents with **inhibitory activity against digestive α-glucosidase enzymes**, supported by in vitro testing and in silico docking, suggesting a potential antihyperglycemic mechanism through delayed carbohydrate digestion and glucose absorption. It is not an approved pharmaceutical product, and no specific commercial developer, manufacturer, standardized formulation, or clinical development program is established from the provided evidence.

Other names
Xeroderris stuhlmannii extractX. stuhlmannii extractxeroderris stuhlmannii phytochemical extract
02

Targets

AMY (Pancreatic alpha-amylase)Sucrase-Isomaltase

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