Drug intelligence / Profile preview

Xia Sang Ju

Development stage
Unknown
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Xia Sang Ju is a traditional Chinese herbal combination used both as a medicinal granule and as an herbal tea. It consists of three main ingredients: Prunellae spica (Prunella vulgaris; "Xia Ku Cao"), Mori folium (Morus alba; "Sang Ye" or mulberry leaf), and Flos Chrysanthemi Indici (Chrysanthemum indicum; "Ye Ju Hua" or wild chrysanthemum). Originating from the classic Qing dynasty formula "Sang Ju Yin," it is commonly used for fever, headache, sore throat, red eyes due to wind-heat in Traditional Chinese Medicine (TCM), and as a general cooling drink. Modern network pharmacology studies suggest that its antihypertensive effects may be mediated by multiple active compounds acting on various targets involved in steroid hormone biosynthesis and aldosterone-regulated sodium reabsorption. The formula demonstrates the TCM principle of “multiple compounds-multiple targets-multiple effects,” with potential benefits for hypertension through modulation of biological processes such as nitrogen compound metabolism[1][2][5].

Brand names
Baiyunshan Xingqun Xia Sang Ju KeliWu Tang Xia Sang Ju Herbal TeaQunXing Xia Sang Ju GranulesXia Sang Ju Chongji Herbal Drink Mix
Other names
XSJxiasangju夏桑菊Chrysanthemum Infusion
02

Targets

GR (Glucocorticoid receptor)ESR2 (ERβ)

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