Drug intelligence / Profile preview

xiakucao xiaoliu mixture

Development stage
Preclinical
Lead developer
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Xiakucao Xiaoliu Mixture is a Traditional Chinese Medicine (TCM) hospital preparation developed by Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, affiliated with the Shanghai University of Traditional Chinese Medicine. Primarily indicated for the treatment of gastric cancer, it is formulated based on the TCM principles of clearing heat, detoxifying, and resolving phlegm to dissipate masses. The mixture's primary active component is derived from *Prunella vulgaris* (Xiakucao). Research suggests its mechanism of action involves the inhibition of the PI3K/Akt signaling pathway and the downregulation of vascular endothelial growth factor (VEGF), which collectively lead to the suppression of tumor cell proliferation, induction of apoptosis, and inhibition of angiogenesis. It is typically used as an adjuvant therapy alongside conventional treatments to improve clinical outcomes and patient quality of life.

Other names
xiakucao xiaoliu mixtureXiakucao Xiaoliu Heji夏枯草消瘤合剂
02

Targets

AKT (RAC-alpha serine/threonine-protein kinase)VEGFA (Vascular endothelial growth factor A)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)

Beyond the preview

Go deeper on xiakucao xiaoliu mixture.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on xiakucao xiaoliu mixture.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call