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xiang-sha-liu-jun decoction

Development stage: Unknown
Lead developer: Xiyuan Hospital
Administration: Oral

Overview

Xiang-sha-liu-jun decoction (XSLJZT) is a traditional Chinese medicine (TCM) herbal formula composed of eight herbs: *Panax ginseng*, *Atractylodes macrocephala*, *Poria cocos*, *Glycyrrhiza uralensis*, *Citrus reticulata*, *Pinellia ternata*, *Aucklandia lappa*, and *Amomum villosum*. It has a centuries-long history of use for treating gastrointestinal disturbances, including vomiting, gastric fullness, and functional dyspepsia. The formula is believed to exert immunomodulatory and anti-inflammatory effects by modulating the Toll-like receptor (TLR) signaling pathway in the gastric mucosa. In clinical research, it has been evaluated as an adjunct to standard triple antibiotic therapy for the eradication of *Helicobacter pylori* in patients with chronic gastritis, particularly those presenting with spleen-stomach qi deficiency.

Other names: Xiangsha Liujunzi DecoctionXiang Sha Liu Jun Zi Decoction

Targets

GHSR (Growth hormone secretagogue receptor)CYP3A4 (Cytochrome P450 3A4)TLR4 (Toll-like receptor 4)

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