Drug intelligence / Profile preview

Xiangtong

Development stage
Unknown
Lead developer
Puyi Biotechnology
Modality
Small Molecules
Administration
Intranasal
01

Overview

Xiangtong is a fully bioabsorbable drug-eluting sinus stent developed by Puyi (Shanghai) Biotechnology. Approved by the CFDA in 2017, it was the first product of its kind to be approved in China. The device is specifically designed for use in patients with chronic sinusitis who have undergone functional endoscopic sinus surgery (FESS). It consists of a biodegradable polymer scaffold that provides mechanical support to maintain the patency of the sinus ostia while locally eluting an anti-inflammatory corticosteroid. This localized drug delivery reduces mucosal inflammation and edema, thereby preventing the formation of postoperative adhesions and synechiae. Because the stent is fully biodegradable, it is naturally absorbed by the body over time, eliminating the need for a secondary surgical procedure for removal.

Brand names
Xiangtong祥通
Other names
Fully Biodegradable Sinus Drug Stent System全降解鼻窦药物支架系统
02

Targets

GR (Glucocorticoid receptor)

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