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Xiao zhong fang granules are a traditional Chinese medicine (TCM) herbal formulation used primarily for the management of conditions such as knee osteoarthritis. The formula is composed of several herbs, including Smilax glabra (20g), Paris polyphylla (10g), Alisma orientale (15g), Plantago (15g), peach kernel (10g), safflower (10g), and radices. The combination is designed to address inflammation, promote circulation, and support joint health according to TCM principles. Its mechanism of action is not defined in terms of modern pharmacological targets but is believed in TCM theory to reduce swelling ("xiao zhong"), resolve stasis, and relieve pain[1]. There are no well-established molecular targets or mechanisms described in Western biomedical literature.
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