Drug intelligence / Profile preview

Xiaoer Dingchuan

Development stage
Preclinical
Lead developer
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Xiaoer Dingchuan is a Traditional Chinese Medicine (TCM) formulation developed by the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, specifically indicated for the treatment of respiratory syncytial virus (RSV) pneumonia in pediatric patients. The preparation is typically administered as granules or an oral liquid and is composed of a complex mixture of herbal extracts, including *Ephedra sinica*, *Scutellaria baicalensis*, and *Prunus armeniaca*. It functions through a multi-target mechanism that includes direct antiviral activity against RSV and potent anti-inflammatory effects. Research conducted by the developing institution suggests that Xiaoer Dingchuan alleviates lung injury and airway inflammation by modulating the TLR4/NF-κB signaling pathway and reducing the production of pro-inflammatory cytokines such as IL-6 and TNF-α. It is primarily utilized as a hospital preparation (院内制剂) within the Liaoning provincial healthcare system.

Brand names
Xiaoer Dingchuan
Other names
Xiaoer Dingchuan FormulaXiaoer Dingchuan KeliXiaoer Dingchuan KoufuyeXiaoer Dingchuan GranulesXiaoer Dingchuan Oral Liquid
02

Targets

TLR4 (Toll-like receptor 4)

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