Drug intelligence / Profile preview

Xiaoer Feire Kechuan oral liquid

Development stage
Phase 2
Lead developer
Sunflower Pharmaceutical Group
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xiaoer Feire Kechuan oral liquid is a traditional Chinese patent medicine formulated for pediatric respiratory conditions. It is composed of eleven herbal ingredients: Ephedra herba (Mahuang), Armeniacae semen amarum (Kuxingren), Gypsum fibrosum (Shigao), Glycyrrhizae radix et rhizoma (Gancao), Lonicerae japonicae flos (Jinyinhua), Forsythiae fructus (Lianqiao), Anemarrhenae rhizoma (Zhimu), Scutellariae radix (Huangqin), Isatidis radix (Banlangen), Ophiopogonis radix (Maidong), and Houttuyniae herba (Yuxingcao). Developed by Heilongjiang Kuihua Pharmaceutical, it is primarily indicated for clearing heat, detoxifying, dispersing the lungs, and resolving phlegm in children suffering from fever, cough, sputum, and asthma caused by wind-heat invading the lungs. It is currently being evaluated in clinical trials for pediatric acute bronchitis.

Brand names
KuihuaXiao Kui Hua小葵花葵花牌
Other names
Xiao'er Feire Kechuan Oral SolutionXiaoer Feire Kechuan oral solution小儿肺热咳喘口服液
02

Targets

AR (Adrenergic receptors)IL8 (C-X-C Motif Chemokine Ligand 8)IL-6 (Interleukin 6)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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