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XiaoErXiaoZhi formula is a Traditional Chinese Medicine (TCM) herbal combination developed by Beijing Hepingli Hospital for the treatment of simple obesity in children. It is specifically indicated for patients presenting with the TCM syndrome of "spleen deficiency and dampness." The formula is designed to tonify the spleen, resolve dampness, and regulate metabolic functions. It is currently being evaluated in a multi-center, randomized, double-blind, placebo-controlled clinical trial (ChiCTR2300068485) to assess its efficacy, safety, and impact on gut microbiota composition in children aged 7 to 14 years. The treatment aims to address pediatric weight gain by modulating metabolic pathways and restoring microbial balance in the gut.
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