Xiaohan Liqi Decoction

Xiaohan Liqi Decoction (XHLQ) is a traditional Chinese medicine (TCM) herbal formula used primarily for its anti-inflammatory effects and modulation of immune and metabolic pathways. Recent pharmacological studies have focused on its use in treating obstructive sleep apnea-hypopnea syndrome (OSAHS), where it has demonstrated efficacy in reducing airway inflammation and modulating key signaling pathways such as PI3K/Akt, HIF-1, TNF-α, and NF-κB. The decoction contains multiple active ingredients including β-sitosterol, palmitoleic acid, α-linolenic acid (ALA), kaempferol, and linoleic acid. These compounds target proteins such as ALB, IL6, CXCL8, HIF1A, IGF1, MMP9, TLR4, NOS3 and PPARG to exert their therapeutic effects. Animal studies confirm that XHLQ can decrease the expression of inflammatory cytokines like IL-6 and TNF-α while downregulating PI3K/Akt pathway activation[1][2].

Brand names

Xiaohan Liqi Granules

Other names

XHLQXiaohan Liqi Granules小寒理气方 (Chinese name)