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Xiaokeqing granule
- Development stage
- Phase 1
- Lead developer
- Tasly Pharmaceutical
- Administration
- Oral
01
Overview
Xiaokeqing granule is a Traditional Chinese Medicine (TCM) herbal formulation developed by The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine. It is currently under clinical investigation for the management of prediabetes and the prevention of progression to type 2 diabetes mellitus. The granule is designed to improve glycemic parameters, including fasting blood glucose, postprandial blood glucose, and HbA1c, while also addressing traditional Chinese medicine syndrome scores related to "Xiaoke" (wasting-thirst syndrome). As a TCM preparation, it likely exerts its therapeutic effects through a multi-component approach to modulate glucose metabolism and insulin sensitivity.
- Brand names
- Xiaokeqing Granules
- Other names
- Xiaokeqing granules消渴清颗粒
02
Targets
FGF2SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)JUN (Transcription factor Jun)NOS3 (eNOS)SRC (Proto-oncogene tyrosine-protein kinase Src)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))HTR2C (5-hydroxytryptamine 2C receptor)SERT (Sodium-dependent serotonin transporter)
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