Drug intelligence / Profile preview

Xiaoshi Gandan granules

Development stage
Unknown
Lead developer
Boji Pharmaceutical Technology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xiaoshi Gandan granules is a traditional Chinese medicine (TCM) formulation currently in Phase III clinical development for the treatment of chronic cholecystitis, specifically for patients presenting with the liver-gallbladder damp-heat syndrome. Developed by Guangzhou Boji New Drug Clinical Research Center, the drug is administered orally as a granule. The therapeutic objective is to alleviate clinical symptoms, primarily right upper quadrant abdominal pain, by addressing the underlying TCM pattern of damp-heat in the liver and gallbladder. As a multi-herb TCM product, its mechanism involves a holistic approach to clearing heat and promoting gallbladder function.

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