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Xiaoshuan enteric-coated capsule (XSECC) is a compound Traditional Chinese Medicine (TCM) preparation derived from the classical formula Buyang Huanwu Decoction (BYHWD). It is approved by the China National Medical Products Administration (NMPA) for the management of stroke and cerebral infarction, specifically to promote brain remodeling and plasticity. The formulation is manufactured by Sanmenxia Sinoway Pharmaceutical. It is currently being investigated in Phase 4 clinical trials for the treatment of fatigue syndrome following cardiovascular and cerebrovascular events, such as myocardial infarction and coronary heart disease treated with percutaneous coronary intervention (PCI). Its mechanism involves neurovascular modulation, including the regulation of Vascular Endothelial Growth Factor (VEGF) and Brain-Derived Neurotrophic Factor (BDNF).
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