Drug intelligence / Profile preview

Xiaotongti analgesic plaster

Development stage
Unknown
Lead developer
奇正藏药
Administration
Topical
01

Overview

Xiaotongti analgesic plaster (also known as Xiaotong Tie Gao) is a Traditional Chinese Medicine (TCM) topical patch primarily developed and manufactured by Tibet Cheezheng Tibetan Medicine. It is formulated with a blend of herbal extracts, including *Herba Meconopsis* (Tibetan poppy), *Radix et Rhizoma Rhei* (Rhubarb), and *Cortex Zanthoxyli* (Prickly ash), which are traditionally used to promote blood circulation, resolve blood stasis, and alleviate pain and swelling. The plaster is widely used in China for the treatment of musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, chronic back pain, and soft tissue injuries. In clinical settings, it has been evaluated for its efficacy in treating refractory plantar fasciitis, often in combination with other therapies like extracorporeal shock wave therapy (ESWT) or nerve blocks. Its mechanism of action involves the inhibition of inflammatory mediators such as cyclooxygenase-2 (COX-2) and various pro-inflammatory cytokines.

Brand names
Cheezheng Xiaotong TieXiaotong Tie
Other names
Xiaotong Tie GaoXiaotong analgesic plaster
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))ALOX5 (Arachidonate 5-lipoxygenase)IL1B (Interleukin-1 beta)NOS2 (Nitric Oxide Synthase 2)

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