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Xiaoyan Granules
- Development stage
- Unknown
- Lead developer
- Jiangyin Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Xiaoyan Granules refers to a group of traditional Chinese medicine (TCM) herbal formulations used for their anti-inflammatory and heat-clearing properties. The specific composition can vary by formulation and manufacturer. For example, Jianwei Xiaoyan Granule (JWXYG) is widely used in China for the treatment of chronic atrophic gastritis and contains multiple herbal components such as albiflorin, paeoniflorin, and lobetyolin[1]. Another variant is Pudilan Xiaoyan granules which include Herba Taraxaci (dandelion), Radix Isatidis (woad root), Indigofera species extracts, baicalin, among others[2]. Mechanistically, these formulations are believed to exert therapeutic effects primarily through inhibition of angiogenesis via regulation of the HIF-1α-VEGF pathway in gastric tissue[1], as well as general anti-inflammatory actions. Some variants are also studied or used for pediatric conditions such as hand-foot-mouth disease or mumps[4][5].
- Brand names
- Xiaoyan Granules
- Other names
- Jianwei Xiaoyan GranuleJWXYGPudilan Xiaoyan granulesHouerhuan Xiaoyan granules
02
Targets
HIF1A (Hypoxia-inducible factor 1-alpha)VEGFR2 (Vascular endothelial growth factor receptor 2)
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