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xiaoyong sanjie decoction
- Development stage
- Preclinical
- Administration
- Oral
01
Overview
Xiaoyong Sanjie Decoction is a traditional Chinese medicine (TCM) herbal compound formula used clinically, particularly in China, for the treatment of inflammatory and neoplastic conditions. It is an empirical prescription composed of multiple herbs, with reported applications in diseases such as anaplastic thyroid cancer (ATC) and ruptured plasma cell mastitis. The decoction's mechanism of action is believed to be multi-targeted, involving anti-inflammatory, antitumor, immune-modulating, and detoxifying effects. Studies have identified active compounds within the formula—such as Saikosaponin A—that may exert antitumor activity by modulating molecular pathways relevant to cancer progression[1][3]. The precise composition can vary but typically includes herbs aimed at clearing heat and toxins, dispersing nodules or masses ("sanjie"), promoting blood circulation, and supporting immune function according to TCM theory.
- Other names
- Xiaoyong Sanjie Tang
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EZH2 (Histone-lysine N-methyltransferase EZH2)
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