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Xiaoyu Anshen
- Development stage
- Unknown
- Lead developer
- Jilin Huakang Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Xiaoyu Anshen is a Traditional Chinese Medicine (TCM) formulation primarily indicated for the treatment of depression, anxiety, and insomnia. It is a multi-herb formula designed to soothe the liver, relieve stagnation, and calm the spirit (Anshen). The preparation typically includes extracts from herbs such as *Radix Bupleuri* (Chaihu), *Radix Angelicae Sinensis* (Danggui), *Poria cocos* (Fuling), *Rhizoma Cyperi* (Xiangfu), and *Semen Ziziphi Spinosae* (Suanzaoren). Pharmacologically, Xiaoyu Anshen is believed to exert its antidepressant and anxiolytic effects by modulating central monoamine neurotransmitter systems, specifically increasing the availability of serotonin and dopamine in the synaptic cleft. Additionally, it has been shown to regulate the hypothalamic-pituitary-adrenal (HPA) axis, thereby mitigating the physiological effects of chronic stress. It is widely utilized in China as both a standalone therapy for mild-to-moderate depression and as an adjuvant to Western antidepressants to improve efficacy and reduce side effects.
- Brand names
- Xiaoyu Anshen KeliXiaoyu Anshen Jiaonang
- Other names
- Jieyu Anshen
02
Targets
DRD (Dopamine receptors)5-HT (Serotonin receptors)
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