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Xiaoyu Jiangzhi capsule
- Development stage
- Unknown
- Lead developer
- Shanghai East Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Xiaoyu Jiangzhi capsule is a Traditional Chinese Medicine (TCM) formulation primarily utilized in China for the management of hyperlipidemia and the prevention of atherosclerosis. The capsule is composed of multiple botanical extracts traditionally indicated to "remove blood stasis" and "lower lipids." Its pharmacological profile includes the modulation of lipid metabolism and the reduction of systemic inflammation. Clinical research, including Phase 4 trials sponsored by institutions such as Shanghai East Hospital, has focused on its application in chronic coronary syndrome (CCS). These studies evaluate the drug's impact on high-sensitivity C-reactive protein (hs-CRP) and other inflammatory and lipid markers, as well as its potential to reduce major adverse cardiovascular and cerebrovascular events (MACCE) and improve quality of life in adult patients.
- Brand names
- Xiaoyu Jiangzhi capsule
- Other names
- Xiaoyu Jiangzhi jiaonangXiaoyu Jiangzhi
02
Targets
CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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