Drug intelligence / Profile preview

Xiaozhong Shengji

Development stage
Unknown
Lead developer
Sichuan Gooddoctor Panxi Pharmaceutical
Administration
Topical, Oral
01

Overview

Xiaozhong Shengji (also known as Xiaozhong Shengji Liquid or GD1802) is a Traditional Chinese Medicine (TCM) preparation developed by Sichuan Good Doctor Panxi Pharmaceutical Co., Ltd. for the treatment of radiation-induced oral mucositis. This condition is a frequent and debilitating side effect of radiotherapy in patients with head and neck cancers, characterized by painful ulcerations and inflammation of the oral mucosa. Xiaozhong Shengji is formulated to reduce swelling, alleviate pain, and accelerate the healing of mucosal tissues. Its mechanism of action involves promoting the proliferation of fibroblasts, enhancing collagen synthesis, and improving local microcirculation, which collectively facilitate the regeneration of damaged epithelial cells. The preparation is typically used as an oral rinse or topical application. It is currently undergoing Phase 2 clinical evaluation in China to establish its efficacy and safety as a specialized supportive care treatment for oncology-related mucosal injury.

Brand names
Xiaozhong Shengji Liquid
Other names
Xiaozhong Shengji Ye消肿生肌液
02

Targets

FGF2TGFB1 (Transforming growth factor Beta-1 proprotein)VEGFA (Vascular endothelial growth factor A)

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