Drug intelligence / Profile preview

Xihuang Capsule

Development stage
Phase 4
Lead developer
Hebei Wanbang Fu Lin Pharmaceutical
Administration
Oral
01

Overview

Xihuang Capsule is an oral traditional Chinese medicine (TCM) formulation used as an adjunctive therapy for various types of cancer. It originated from a classic formula known as Xihuang Wan (Pill) from the Qing dynasty. [2, 9] The capsule form is considered a modern version with potentially better absorption. [9] It is composed of four main ingredients: Calculus bovis (cattle bezoar), Moschus (musk), Myrrh, and Olibanum (frankincense). [2, 4] In TCM theory, its functions are to clear heat, resolve toxicity, reduce swelling, and invigorate blood to dissipate nodules. [4] Modern research and clinical trials are investigating its efficacy in combination with conventional cancer treatments like chemotherapy and immunotherapy. Studies suggest it possesses multiple anti-tumor properties, including inhibiting cancer cell proliferation and angiogenesis, inducing apoptosis, and modulating the tumor immune microenvironment. [2] It is used for various cancers, including breast, liver, lung, and prostate cancer. [1, 2, 18]

Brand names
Xihuang WanTongrentang Xihuang Wan
Other names
Xihuang Jiao Nang西黄胶囊
02

Targets

HSP90 (Heat shock protein 90 chaperone complex)ESR1 (ERα)

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