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Xihuang pill

Development stage: Unknown
Lead developer: Affiliated Hospital of Jiangnan University
Administration: Oral

Overview

Xihuang pill (Xihuang Wan) is a traditional Chinese medicine (TCM) formula widely utilized in China as an adjuvant therapy for various malignancies, including breast cancer, liver cancer, and cholangiocarcinoma. The formula typically consists of four primary ingredients: Calculus Bovis (Niu Huang), Moschus (She Xiang), Boswellia carterii (Ru Xiang), and Commiphora myrrha (Mo Yao). It is recognized for its anti-tumor, anti-inflammatory, and immunomodulatory properties. Mechanistically, Xihuang pill is thought to inhibit tumor cell proliferation, induce apoptosis, and modulate the immune microenvironment, potentially enhancing the efficacy of modern treatments like chemotherapy and immunotherapy while mitigating treatment-related toxicity.

Brand names: Xihuang Wan
Other names: XihuangwanXi Huang Wan

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)PDCD1 (Programmed cell death protein 1 receptor)

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