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Xijiao Dihuang Decoction

Development stage: Preclinical
Administration: Oral

Overview

Xijiao Dihuang Decoction is a traditional Chinese medicine formula used to treat severe fevers, heat in the blood system, and blood stagnation. It consists of four herbs: Water Buffalo Horns (Shui Niu Jiao), Rehmannia glutinosa, Paeonia lactiflora, and Paeonia suffruticosa. The formula is known for clearing heat, cooling blood, and dispersing blood stasis. It has been studied for its potential in treating conditions like psoriasis and sepsis.

Other names: Rhinoceros and Rehmannia Decoction犀角地黄汤

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)MMP9 (Matrix metalloproteinase-9)NF-κBVEGFA (Vascular endothelial growth factor A)TLR4 (Toll-like receptor 4)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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