Drug intelligence / Profile preview

Xilda-M100

Development stage
Unknown
Lead developer
Dios Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Xilda-M100 is a fixed-dose combination pharmaceutical product developed by Dios Lifesciences for the management of type 2 diabetes mellitus. It contains two active ingredients: vildagliptin (50 mg) and metformin hydrochloride (1000 mg), formulated as a sustained-release tablet. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of incretin hormones, which in turn stimulates glucose-dependent insulin secretion and suppresses glucagon release from the pancreas. Metformin is a biguanide that improves glycemic control by reducing hepatic glucose production, decreasing intestinal glucose absorption, and enhancing peripheral insulin sensitivity. This combination is typically prescribed when diet, exercise, and monotherapy with either agent are insufficient to achieve target blood sugar levels.

Brand names
Xilda-M100Xilda-M-100Xilda-M 100
Other names
vildagliptin + metformin 50mg/1000mgvildagliptin 50mg + metformin 1000mg
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)DPP-4 (Dipeptidyl Peptidase-IV)ND1 (Mitochondrial electron transport chain complex I)

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