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Xin Kai Ku Jiang formula is a traditional Chinese medicine (TCM) formula composed of twelve herbal ingredients: Pinellia ternata, Scutellaria baicalensis, Coptis chinensis, Fructus Evodiae, Radix Pseudostellariae, Perilla frutescens, Radix Paeoniae Alba, Magnolia officinalis, Fritillaria thunbergii, Turmeric, Bupleurum chinense, and Fructus Aurantii. It is being investigated in a randomized controlled trial for the intervention of visceral sensitivity in patients with non-erosive gastroesophageal reflux disease combined with anxiety and depression. The formula is administered orally as granules.
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