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Xingxiao pill
- Development stage
- Unknown
- Lead developer
- PLA General Hospital Seventh Medical Center
- Administration
- Oral
01
Overview
Xingxiao pill (Xingxiao Wan) is a Traditional Chinese Medicine (TCM) formulation traditionally used in oncology for its purported ability to resolve swelling, dissipate masses, and promote blood circulation. It is a classic formula often composed of ingredients such as Frankincense (Ru Xiang), Myrrh (Mo Yao), Realgar (Xiong Huang), and Musk (She Xiang). In clinical practice, it is utilized for the treatment of various tumors and nodules. Recent clinical research, including prospective randomized controlled trials, has focused on its role as an adjuvant therapy for small cell lung cancer (SCLC), specifically to evaluate its efficacy and safety when administered during intermittent chemotherapy cycles to improve patient outcomes and mitigate treatment-related toxicity.
- Brand names
- Xingxiao pill
- Other names
- Xingxiao WanXing Xiao Wan
02
Targets
Smoothened (SMO) / GLI family zinc finger 1 (GLI1) / SRY-box transcription factor 2 (SOX2) axisSREBP-1 / SREBF1 (SREBP-1)GR (Glucocorticoid receptor)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)ESR1 (ERα)PLA2G4A (Cytosolic phospholipase A2 alpha)
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