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Xinyihua nano-extract hydrogel
- Development stage
- Unknown
- Lead developer
- Chinese PLA General Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Intranasal
01
Overview
Xinyihua nano-extract hydrogel is a botanical-based nasal formulation developed by the Chinese PLA General Hospital for the treatment of allergic rhinitis. The active component is derived from Magnolia flos (Xinyihua), a traditional Chinese medicine known for its anti-inflammatory and anti-allergic properties. This specific formulation utilizes nanotechnology to create a nano-extract, which is then incorporated into a hydrogel base to enhance drug delivery, prolong contact time with the nasal mucosa, and improve therapeutic efficacy. It is currently being evaluated in Phase 1 clinical trials to assess its safety and efficacy in adults with mild allergic rhinitis.
- Other names
- Magnolia flos nano-extract hydrogelXinyihua nano-extract hydrogel nasal drops
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