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Xinyu patch is a traditional Chinese medicine (TCM) based bioadhesive patch developed by researchers at Zhejiang University, specifically for the treatment of recurrent aphthous ulcers (RAU). The formulation typically incorporates natural active ingredients such as *Indigo naturalis* (Qingdai) and *Borneolum syntheticum* (Bingpian). The patch is designed for topical application to the oral mucosa, where it forms a protective physical barrier over the ulcerated tissue. Its therapeutic action is mediated through the local release of anti-inflammatory and analgesic compounds that suppress pro-inflammatory cytokines (e.g., TNF-α, IL-6) and promote the migration of epithelial cells for faster wound closure. It is primarily used to alleviate pain and shorten the healing time of oral ulcers.
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