Drug intelligence / Profile preview

Xirconi

Development stage
Unknown
Lead developer
Ferozsons Group
Modality
Small Molecules
Administration
Topical
01

Overview

Xirconi is a topical antifungal cream containing 1% oxiconazole nitrate, developed and marketed by Ferozsons Laboratories Limited. As an imidazole derivative, oxiconazole nitrate exerts its antifungal effect by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, primarily through the inhibition of the enzyme lanosterol 14-alpha-demethylase. This disruption leads to increased membrane permeability and fungal cell death. Xirconi is indicated for the treatment of various dermatological fungal infections, including tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea versicolor, as well as cutaneous candidiasis. It is formulated for external dermatologic application and is typically applied once or twice daily to the affected areas.

Brand names
Xirconi
Other names
oxiconazole nitrate
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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