Drug intelligence / Profile preview

XOB

Development stage
Unknown
Lead developer
Alexander Shulgin Research Institute
Modality
Small Molecules
01

Overview

XOB is a synthetic compound known chemically as N-[(4-phenylbutoxy)hexyl]-4-bromo-2,5-dimethoxyphenethylamine. It acts as a serotonin 5-HT2A receptor antagonist and also blocks voltage-gated sodium channels. These dual actions suggest potential effects on both neurotransmission and neuronal excitability, but there is no evidence of clinical development or approved medical use for this compound. Its primary relevance appears to be in research settings related to neuropharmacology[1].

Other names
N-[(4-phenylbutoxy)hexyl]-4-bromo-2,5-dimethoxyphenethylamine
02

Targets

NaV (Voltage-gated sodium channels)HTR2A (Serotonin receptor 5-HT2A)

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