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XTR003 + 18F-FDG
- Development stage
- Phase 2
- Lead developer
- Sinotau Pharmaceutical Group
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
XTR003 + 18F-FDG is a **combination diagnostic imaging agent** used in positron emission tomography (PET). **18F-FDG** (fludeoxyglucose F 18) is a radiolabeled glucose analog that accumulates in cells with high glucose metabolism, notably cancer cells, and is widely used as a PET imaging tracer in oncology, cardiology, and neurology[2][3][4][5]. XTR003 is a code name for an investigational agent; however, its specific mechanism, chemical identity, and development status are not characterized in available literature. The combination is intended to improve imaging by targeting both metabolic and possibly additional pathological features, but the mechanism specifically attributed to XTR003 is not described in the available data.
- Other names
- fludeoxyglucose F 18fluorodeoxyglucose F 18FDG
02
Targets
GLUT1 (Glucose transporter 1)SLC2A3 (Glucose transporter type 3)GCK (Glucokinase)GLUT (Glucose transporter family)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)
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