Xuanfei Baidu formula

Xuanfei Baidu formula (also known as Xuanfei Baidu decoction or granules) is a traditional Chinese medicine (TCM) herbal formulation developed by Academician Boli Zhang and Professor Qingquan Liu. It is composed of 13 medicinal herbs, including Ephedrae Herba, Armeniacae Semen Amarum, Gypsum Fibrosum, Coix Seed, Atractylodis Rhizoma, Pogostemonis Herba, Polygoni Cuspidati Rhizoma et Radix, Verbenae Herba, Phragmitis Rhizoma, Descurainiae Semen, Citri Grandis Exocarpium, Artemisiae Annuae Herba, and Glycyrrhizae Radix et Rhizoma. Xuanfei Baidu formula was approved by the National Medical Products Administration (NMPA) of China in March 2021 for the treatment of COVID-19, specifically for patients with mild or moderate dampness-toxin obstructing lung syndrome. It is also being evaluated for other respiratory and inflammatory conditions, including influenza A, chronic obstructive pulmonary disease (COPD), systemic inflammatory response syndrome (SIRS), and acute lung injury (ALI). The formula exerts its therapeutic effects through multi-component, multi-target pathways, demonstrating anti-inflammatory, immunomodulatory, and antiviral activities, particularly by modulating the NF-κB, MAPK, and JAK/STAT signaling pathways, and regulating gut microbiota homeostasis.

Brand names

Xuanfei Baidu Granules

Other names

XFBDXuanfei BaiduXuanfei Baidu GranuleXuanfei Baidu decoctionXuanfei Baidu formula宣肺败毒方宣肺败毒颗粒