Drug intelligence / Profile preview

xuanfei zhisou compound

Development stage
Unknown
Lead developer
Gansu Puan Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xuanfei Zhisou compound (also known as Xuanfei Zhisou Heji) is a Traditional Chinese Medicine (TCM) formulation primarily used for the treatment of cough, including post-infectious cough and cough associated with acute or chronic bronchitis. Its therapeutic actions are characterized in TCM as ventilating the lung (Xuanfei), resolving phlegm, and suppressing cough (Zhisou). The formulation is a complex mixture of several herbal extracts, typically including *Schizonepeta tenuifolia*, *Peucedanum praeruptorum*, *Platycodon grandiflorus*, *Aster tataricus*, *Tussilago farfara*, *Citrus reticulata*, and *Glycyrrhiza uralensis*. It is widely utilized in clinical practice in China and has been the subject of large-scale real-world safety and efficacy studies to evaluate its adverse drug reaction profile and clinical utility.

Brand names
Xuanfei Zhisou Heji
Other names
Xuanfei Zhisou MixtureXuanfei Zhisou Heji宣肺止嗽合剂
02

Targets

IL-17A (Interleukin-17A)ADRB2 (β2)

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