Drug intelligence / Profile preview

Xuanfei Zhisou Heji

Development stage
Unknown
Lead developer
Gansu Puan Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xuanfei Zhisou Heji is a standardized traditional Chinese medicine (TCM) preparation developed by Gansu Pu'an Pharmaceutical Co., Ltd. It is a complex herbal formulation containing eight active botanical ingredients: *Aster tataricus*, *Stemona sessilifolia*, *Platycodon grandiflorus*, *Citrus reticulata*, *Houttuynia cordata*, *Papaver somniferum* husk, *Glycyrrhiza uralensis*, and *Ephedra sinica*. The preparation is indicated for the treatment of respiratory conditions, including post-infectious cough, cough variant asthma, and bronchitis, by dispelling wind, promoting lung circulation, and resolving phlegm. It has also been investigated for managing cough symptoms associated with COVID-19.

Brand names
Xuanfei Zhisou Heji
Other names
Xuanfei Zhisou mixtureXZM宣肺止嗽合剂
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)IL-6 (Interleukin 6)

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