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Xuebi Formula
- Development stage
- Unknown
- Lead developer
- Guang'anmen Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Xuebi Formula is a Traditional Chinese Medicine (TCM) herbal prescription developed by Guang'anmen Hospital of the China Academy of Chinese Medical Sciences. It is specifically formulated to treat diabetic peripheral neuropathy (DPN) in patients presenting with the 'Qi Deficiency and Blood Stasis' syndrome. In TCM theory, DPN is often categorized as a 'Bi syndrome' characterized by numbness or pain, and this formula aims to tonify Qi and invigorate blood circulation to alleviate symptoms such as sensory loss and pain in the extremities. The formula is typically evaluated in clinical settings as an oral decoction or granule preparation, comparing its efficacy against placebo in improving nerve conduction velocity and clinical symptom scores.
- Brand names
- Xuebi formula
- Other names
- Xuebi PrescriptionXuebi Decoction
02
Targets
HMGB1 (High mobility group protein B1)Cyp (Cyclophilin family)MEK
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