Drug intelligence / Profile preview

Xuelian Injection

Development stage
Unknown
Lead developer
Xinjiang Yindolan Pharmaceutical
Administration
Intravenous, Intramuscular
01

Overview

Xuelian Injection is a traditional Uighur medicine extract derived from *Saussurea involucrata* (Tianshan snow lotus). Developed by Xinjiang Yinduolan Uighur Medicine, it is an injectable herbal product used primarily for the treatment of rheumatoid arthritis and cerebral ischemia-reperfusion injury. The preparation contains active compounds such as chlorogenic acid and rutin. Its pharmacological action is characterized by anti-inflammatory effects, specifically through the inhibition of the Toll-like receptor 4 (TLR4) signaling pathway, which leads to a reduction in inflammatory mediators like TNF-α, IL-1β, and MMP-9. It has been used clinically in China for approximately twenty years and is approved for use in Chinese hospitals.

Brand names
雪莲注射液Xuelian Injection
Other names
Tianshan Snow Lotus InjectionSaussurea Involucrata Injection
02

Targets

IL1B (Interleukin-1 beta)MMP9 (Matrix metalloproteinase-9)TNFA (Tumor necrosis factor alpha (soluble))TLR4 (Toll-like receptor 4)

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