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Xueping tablet
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Xueping tablet is a Traditional Chinese Medicine (TCM) preparation indicated for the treatment of abnormal uterine bleeding (AUB). It is administered orally in tablet form. Its therapeutic effects are attributed to its ability to clear heat, remove blood stasis, stop bleeding, and regularize menstruation. Mechanistically, Xueping tablet has been shown to inhibit the inflammatory response mediated by the VEGF-ERK1/2 pathway. This involves reducing the expression levels of various inflammatory factors and matrix metalloproteinases, such as VEGF, p-ERK, NF-κB, SAA, MMP-2, MMP-9, TIMP-1, TIMP-2, and TIMP-3, while also increasing progesterone levels. The drug is manufactured by Jiangxi Puzheng Pharmaceutical Co., Ltd.
- Other names
- 血平片XPT
02
Targets
TIMP3 (Tissue inhibitor of metalloproteinases 3)TIMP1 (Metalloproteinase inhibitor 1)NF-κBMMP9 (Matrix metalloproteinase-9)VEGFA (Vascular endothelial growth factor A)MMP2 (Matrix metalloproteinase-2)TIMP2MAPK3 (Mitogen-activated protein kinase 1)
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