Drug intelligence / Profile preview

Xueshuanxinmaining tablets

Development stage
Phase 4
Lead developer
Jilin Huakang Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Xueshuanxinmaining tablets (marketed under the brand name Tianxintai) is a traditional Chinese patent medicine developed by Jilin Huakang Pharmaceutical for the treatment of cardiovascular and cerebrovascular diseases. It is formulated from ten traditional Chinese medicinal ingredients, including Ligusticum chuanxiong, Salvia miltiorrhiza, leech, holly, artificial bezoar, artificial musk, Sophora japonica, ginseng stem and leaf saponins, borneol, and toad venom. The formulation is designed to replenish qi, promote blood circulation, induce resuscitation, and relieve pain. It is primarily indicated for the recovery phase of ischemic stroke (cerebral infarction) and coronary heart disease angina pectoris characterized by qi deficiency and blood stasis.

Brand names
Tian Xin TaiTianxintai
Other names
Tian Xin Tai Xueshuanxinmaining tabletsTianxintai Xueshuanxinmaining tabletsXue Shuan Xin Mai Ning PianXueshuan XinmainingXueshuan Xinmaining tabletsXueshuanxinmainingXueshuanxinmaining PianXueshuanxinmaining tablets
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)CA1 (Carbonic anhydrase 1)FXIIIa (Coagulation factor XIII A subunit)VEGFR2 (Vascular endothelial growth factor receptor 2)KEAP1 (Kelch-like ECH-associated protein 1)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)NFKB1 (NF-κB1)SRC (Proto-oncogene tyrosine-protein kinase Src)VEGFA (Vascular endothelial growth factor A)

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