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xuezhitong jiaonang
- Development stage
- Phase 4
- Lead developer
- Jilin Oriental Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Xuezhi Tong Capsules (血滞通胶囊) is a Traditional Chinese Medicine (TCM) product developed and manufactured by Jilin Province Oriental Pharmaceutical. The formulation is primarily composed of an extract from *Allium macrostemon* Bunge (Xiebai). It is indicated for the treatment of hyperlipidemia, particularly in patients exhibiting TCM syndromes of phlegm-stasis resistance. The therapeutic mechanism involves activating blood circulation, resolving phlegm, and dredging collaterals, which collectively help to lower elevated serum cholesterol and triglycerides. By improving lipid metabolism and blood flow, it is used to manage blood circulation disorders and potentially mitigate the progression of atherosclerosis. It is an oral medication approved for marketing in China.
- Brand names
- Xuezhi Tong血滞通
- Other names
- Xuezhi Tong Capsules血滞通胶囊Xuezhitong Jiaonang
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)DGAT2 (Hepatic diacylglycerol acyltransferase 2)MAPK3 (Mitogen-activated protein kinase 1)GPX1 (Glutathione peroxidase 1)HMOX1 (Heme oxygenase 1)NOX4 (NADPH oxidase 4)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)SREBP-1 / SREBF1 (SREBP-1)
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