Drug intelligence / Profile preview

xyloglucan + pea protein

Development stage
Unknown
Lead developer
Novintethical Pharma
Modality
Recombinant Proteins and Enzymes
Administration
Oral, Topical
01

Overview

Xyloglucan + pea protein is a natural product combination developed by Devintec SAGL for the management of gastrointestinal and dermatological disorders. The combination consists of xyloglucan, a polysaccharide derived from tamarind seeds (*Tamarindus indica*), and pea protein from *Pisum sativum*. It functions as a mechanical barrier protector (a "bio-barrier") that coats mucosal and epithelial surfaces. This protective film prevents the adhesion and penetration of pathogens and allergens while promoting the restoration of tight junction proteins, including ZO-1, occludin, and claudin-1. Clinically, it is used for conditions such as atopic dermatitis, where it has shown efficacy comparable to low-potency corticosteroids, and for gastrointestinal issues like irritable bowel syndrome with diarrhea (IBS-D) and functional bloating. It is approved in Europe as a medical device for restoring intestinal barrier integrity.

Brand names
GelsectanXilaplus
Other names
XG-PPxyloglucan and pea protein
02

Targets

OCLN (Occludin)TJP1 (Tight junction protein 1 (ZO-1))CLDN1 (Tight junction protein claudin-1)

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