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Yang02 probiotic

Development stage: Unknown
Lead developer: Dermatology Hospital of Southern Medical University
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

Yang02 probiotic is an oral microbial therapy being evaluated for the treatment of moderate to severe acne vulgaris. Developed and studied by the Dermatology Hospital of Southern Medical University, it is part of a clinical program investigating the gut-skin axis. The probiotic is intended to modulate the gut microbiota, reduce systemic inflammation, and decrease sebum secretion, thereby reducing the count of inflammatory and non-inflammatory acne lesions. It is currently being studied in a Phase 4 exploratory trial both as a monotherapy and in combination with Yang03 probiotic.

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