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Yangjing Zhongyu Decoction
- Development stage
- Unknown
- Lead developer
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
- Administration
- Oral
01
Overview
Yangjing Zhongyu Decoction is a traditional Chinese medicine (TCM) formula originally recorded in the Qing Dynasty text *Fu Qing Zhu Nu Ke* (Fu Qing-zhu's Gynecology). It is primarily used to treat female infertility associated with Kidney-yin deficiency and Blood deficiency. The classic formulation consists of four herbs: *Rehmannia glutinosa* (Shu Di Huang), *Angelica sinensis* (Dang Gui), *Paeonia lactiflora* (Bai Shao), and *Cornus officinalis* (Shan Zhu Yu). In modern clinical practice, it is frequently investigated for its potential to improve endometrial receptivity, enhance ovarian function, and support reproductive outcomes in conditions such as endometriosis-associated infertility, diminished ovarian reserve (DOR), and polycystic ovary syndrome (PCOS), particularly in patients undergoing assisted reproductive technologies like IVF/ICSI.
- Other names
- Yangjing Zhongyu TangYǎng Jīng Zhòng Yù Tāng养精种玉汤
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR1 (ERα)TAK1 (Transforming growth factor beta–activated kinase 1)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)VEGFA (Vascular endothelial growth factor A)ER (Estrogen receptor)PR (Progesterone receptor)
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