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Yangxue Qufeng Zhitong granules (previously known as Nuolitong Granules during development) is a Class 1.1 innovative traditional Chinese medicine (TCM) developed by Hunan Fangsheng Pharmaceutical through its wholly-owned subsidiary, Guangdong Fangsheng Jianmeng Pharmaceutical. The formulation is a multi-herb TCM preparation composed of Astragali Radix, Angelicae Sinensis Radix, Codonopsis Radix, bran-fried Atractylodis Macrocephalae Rhizoma, Chuanxiong Rhizoma, Saposhnikoviae Radix, Cimicifugae Rhizoma, Bupleuri Radix, Menthae Haplocalycis Herba, Schizonepetae Herba, Notopterygii Rhizoma et Radix, and Angelicae Dahuricae Radix. It is developed by modifying Zhang Xichun's Shengxian Decoction. The drug is indicated for the treatment of frequent episodic tension-type headache, which TCM classes as Qi and Blood Deficiency Syndrome. It was approved for marketing in China in June 2025 and added to China's National Reimbursement Drug List in December 2025.
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