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Yangyin Shugan

Development stage: Unknown
Lead developer: Guangdong Provincial Hospital of Traditional Chinese Medicine
Administration: Oral

Overview

Yangyin Shugan is a Traditional Chinese Medicine (TCM) herbal formula developed by the Guangdong Provincial Hospital of Chinese Medicine for the treatment of climacteric (menopausal) depression. The formula is designed to nourish Yin and soothe the liver, addressing the emotional and endocrine imbalances associated with menopause. Clinical research, including trial ChiCTR2200060333, evaluates its efficacy when used in combination with acupuncture (frontal or spinal). The mechanism of action is hypothesized to involve the modulation of the brain-gut axis, regulation of neurotransmitters, and stabilization of the reproductive endocrine system.

Brand names: Yang Yin Shu Gan
Other names: Yangyin Shugan formula

Targets

ESR2 (ERβ)ESR1 (ERα)

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