Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Yangzhengxiaoji Capsule
- Development stage
- Unknown
- Lead developer
- Yiling Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yangzhengxiaoji Capsule (YZXJ) is a complex traditional Chinese medicine (TCM) formulation developed by Shijiazhuang Yiling Pharmaceutical, primarily used as an adjuvant therapy for various malignancies, including hepatocellular carcinoma and non-small cell lung cancer (NSCLC). The formulation consists of multiple herbal components that collectively exert anti-tumor effects by antagonizing the hepatocyte growth factor (HGF) and its receptor, c-MET, which are critical drivers of cancer cell migration, invasion, and angiogenesis. Furthermore, YZXJ has been shown to inhibit the focal adhesion kinase (FAK) signaling pathway, contributing to its anti-metastatic properties. In clinical practice, it is frequently administered alongside standard platinum-based chemotherapy to enhance therapeutic efficacy, improve patient quality of life, and manage chemotherapy-induced side effects. It is currently being evaluated in Phase 4 clinical trials for advanced NSCLC in China.
- Brand names
- Yangzhengxiaoji
- Other names
- YangZheng XiaoJiYangzhengxiaoji formula
02
Targets
FAK (Focal adhesion kinase)HGF (Hepatocyte growth factor)MET (Mesenchymal-epithelial transition factor receptor)
Beyond the preview
Go deeper on Yangzhengxiaoji Capsule.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Yangzhengxiaoji Capsule.