Drug intelligence / Profile preview

Yanhuning

Development stage
Unknown
Lead developer
Changjiang Pharmaceutical
Modality
Small Molecules
Administration
Intravenous, Injection
01

Overview

Yanhuning is a Traditional Chinese Medicine Injection (TCMI) derived from the plant Andrographis paniculata (Chuanxinlian), with its active component being an andrographolide derivative. It is globally approved for infectious diseases and virus diseases. It is widely used in China, often in combination with conventional Western medicine, for the treatment of various infectious and inflammatory conditions, particularly in children. Clinical studies and network meta-analyses have investigated its efficacy in conditions such as bronchopneumonia, Mycoplasma pneumoniae pneumonia, acute upper respiratory tract infection, rotavirus enteritis, influenza, acute tonsillitis, community-acquired pneumonia, acute bronchitis, and COVID-19. Its known mechanisms include inhibiting *Candida albicans* biofilms by downregulating adhesion-related genes like ALS1, ALS3, HWP1, EAP1, and MP65. It also exhibits broader anti-inflammatory and antiviral properties, contributing to its therapeutic effects in respiratory and other infections.

Brand names
YanhuningInjectable Yanhuning炎琥宁炎琥宁注射液
Other names
Yanhuning Injection
02

Targets

Als3 (Agglutinin-like sequence protein 3)IRF2BPL (Probable E3 ubiquitin-protein ligase IRF2BPL)MP65 (Cell surface mannoprotein MP65)HWP1 (Hyphal wall protein 1)SOD (Manganese Superoxide Dismutase)

Beyond the preview

Go deeper on Yanhuning.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Yanhuning.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call